Pharmacokinetics of ciprofloxacin in sheep after single intravenous or intramuscular administration
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چکیده
منابع مشابه
Pharmacokinetics of Cefepime Following Intravenous and Intramuscular Administration in Sheep
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متن کاملPharmacokinetics of enrofloxacin after single intravenous administration in sheep.
The disposition of enrofloxacin in sheep was investigated after single-dose intravenous administration of 2.5 mg/kg body weight. Blood samples were drawn from the jugular vein at predetermined times after drug administration. Plasma concentrations of enrofloxacin and its active metabolite ciprofloxacin were simultaneously determined by reverse-phase high performance liquid chromatography. The d...
متن کاملPharmacokinetics of diclofenac in sheep following intravenous and intramuscular administration.
OBJECTIVES The aim of this work was to examine the pharmacokinetics of diclofenac (DCLF) in sheep after intravenous (IV) and intramuscular (IM) dosing. ANIMALS Healthy male Najdi sheep. MATERIALS AND METHODS Diclofenac (1 mg kg(-1)) was administered to ten clinically healthy-male Najdi sheep IV or IM (n = 5 each). Blood samples (5 mL) were collected and serum was separated for drug analysis...
متن کاملPharmacokinetics of tetracycline hydrochloride after single intravenous injection in dogs
Six mixed-breed apparently healthy dogs were intravenously administered a single dose of tetracycline hydrochloride (50 mg/kg) to evaluate the pharmacokinetic parameters of the drug. Blood samples were collected before and at various time intervals after the administration of the drug. Serum tetracycline concentrations were determined over a 24 h period using fluorescence spectrophotometry. Non...
متن کاملPharmacokinetics of isepamicin following a single administration by intravenous infusion or intramuscular injections.
The pharmacokinetics of isepamicin following administration of a 1-g dose were evaluated for 18 healthy male volunteers between the ages of 26 and 38. In a randomized crossover fashion, each volunteer received doses of isepamicin by a 30-min intravenous infusion and as an intramuscular injection. Blood samples were collected at specified times after dosing and assayed for isepamicin by a valida...
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ژورنال
عنوان ژورنال: Veterinary Quarterly
سال: 1996
ISSN: 0165-2176,1875-5941
DOI: 10.1080/01652176.1996.9694613